Published Paper Details:

Lozenges are palatable unit dosage form administrated in the oral cavity, which is the most common route and easiest way of administering a drug and have a bright future as novel method of delivering drugs for local and systemic effect. Lozenges are solid preparations that contain one or more medicaments, usually in a flavoured, sweetened base, and are intended to dissolve or disintegrate slowly in the mouth. The main objective present study to formulate medicated lozenges by useing isomalt sugar.The physical characteristics of the tablets were relatively stable after half a year storage at different humidities as a result of the low hygroscopicity of isomalt.Isomalt is a sugar substitute with a wide range of potential pharmaceutical applications as a result of its physicochemical properties.The benefits of the medicated lozenges is they increase theretention time of the dosage form in oral cavity which increases bioavailability, reduces gastric irritation and bypasses first pass metabolism. The acceptance for lozenges as a dosage form is high by adults and also more by children.