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NFIT i.e., Needle-free injection technology is a comprehensive concept that covers an array of drug delivery systems designed to transport medications through the skin without the need for hypodermic needles. These systems utilize different forces, including Lorentz forces, shock waves, gas pressure or electrophoresis, to eliminate the necessity of using needles for drug administration. This method offers benefits not limited to the pharmaceutical sector, the emerging nations also finds it extremely helpful in mass vaccination campaigns by diminishing the likelihood of needle-related injuries and averting additional associated repercussions, such as those brought on by the repeated use of a single needle. Based on how they operate, the kind of load they carry, how drugs are delivered, and where they are delivered, NFIT devices can be categorized. The key considerations for ensuring a reliable, secure, and efficient drug delivery using NFIT are the drug's viscosity, sterility and shelf life of the medication. Another notable advantage of this technology is its capability to deliver highly viscous medication formulations that are challenging to administer using traditional needle and syringe systems, particularly when employing advanced needle-free injection systems. Needle-free injection technology devices are Produced using various techniques; however, the most used method is the injection molding technique. This technology is being offered in a variety of forms, including Vitajet 3, Tev-Tropin, Bioject ZetaJetTM and others. Numerous devices are already on the market as a result of greater investment in its development and FDA approval.