Published Paper Details:

In the present study mouth dissolving tablets of ranolazine were designed, prepared and evaluated. These tablets can disintegrate or dissolve rapidly once placed into the oral cavity. The drug was analyzed for its organoleptic, physicochemical and spectral properties. The obtained ranolazine was concordant with reference specifications. A complex of was successfully formulated. Mouth dissolving tablet was prepared by addition of superdisintegrants (Sodium starch glycolate and Crospovidone). The tablets were evaluated for their organoleptic (Color, Odor, Taste), physical (Size, Shape and Texture) and quality control parameters (Diameter,Thickness, Hardness, Friability, Disintegration Time and Wetting Time). The goal of this investigation has been achieved by preparing fast drug delivery technique of ranolazine with the aid of super disintegrating agents. The superdisintegrants that affect disintegration time and percentage friability.