Published Paper Details:

Kampavata is one of the vatavyadhi, Basavarajeeyam gives a brief description of this with symptoms such as Kara pada tala kampa, Deha brahmana, Nidrabhanga, Matiksheena, etc. Kampavata can be correlated to Parkinson's disease. It is a neurodegenerative disease. It is a progressive loss of structure or functions of neurons including the death of neurons ranging from molecular to the systemic level. Tremor, rigidity, and bradykinesia are the main symptoms of Parkinson's disease; these symptoms are similar to Kampa, Sanga, and Gatisanga. These are mainly because of Vata. Here Vata Dosha is responsible for the disease which is originating either in Sakha, Koshta, Marma, Asthi, or Sandhi. A mixture of Saindhava and Madhu generates the hydroelectric energies in nerve cells for communication. Due to the Sukshma property of Sneha, it helps the drug to reach the microcellular level. The medicinal value of Kalka and Kwatha helps with curative, purification, and preventive aspects. Basti acts as a regenerative process. Its Veerya helps to disrupt the pathogenic process and carries out the morbid matter towards Pakvashaya for elimination, there after by absorption it starts its regenerative process. The clinical trial was undertaken to compare the efficacy of Matra Basti with Masha Taila and Ksheerabala Taila 7 aavarthita in the management of Kampavata (Parkinson's Disease). 30 patients having classical symptom of Kampavata of either sex were selected and divided into two groups; consisting of 15 patients in each group. In Group-A Matra Basti was administered with Masha Taila in dose of 60ml was inserted through rectum for 9 consecutive days. In Group-B Matra Basti was administered with Ksheerabalataila 7 aavarthita in dose of 60ml was inserted through rectum for 9 consecutive days. The clinical assessment was done using Modified Universal Parkinson's Disease Rating Scale. All symptoms were given scoring depending upon their severity from 0 to 4. The results were subjected to Wilcoxon signed rank test and Mann Whitney U Test Rank it suggests no significant difference after the treatment. Overall the results are not much better in both groups. So far, the experience with treatment has been good and the response is up to 25% in all the patients of both groups.