Published Paper Details:

In last decade the use of biomarker is increased as early warning system in the evaluation of disease risk. In recent years, biomarkers plays an important role in the identifying the drug's mechanism of action, investigation of toxicity and patients response. Biomarkers used in clinical practice to personalize medication or healthcare. They are created by organs suffers with disease or body in response to various disease. The biomarkers are targeted to improve the diagnosis, prognosis, and therapeutics. The identification of ideal biomarkers holds the keep potential for personalized medicine and clinical outcomes. Clinical trials are essential for the improvement of healthcare and advancement of Medical Sciences. In this review, we discuss the history, various definitions, classifications, characteristics and discovery of biomarkers. The use of biomarkers for clinical applications depends on their efficacy in terms of disease diagnosis, disease staging, and treatment selection. The aim of the present review to inspire the reader to investigate the new approaches in biomarker research and development.