Published Paper Details:

It is group of studies that before the formulation and development of any dosage form. In The preformulation mainly studied the Physiochemical properties and nature of API & excipient. In preformulation studied provide important information for design formulation.& need for molecular modification. Every drug has their intrinsic / different physical and chemical properties which are consider before the development of the drug. study of drug -excipient compatibility is an important phase in pre-formulation stage in drug development main objective of the preformulation is to The develop elegant safe stable and effective dosage form. Also studied the physical properties such. As physical form (crystalline , Amorphous) particle size, shape, flow properties, solubility profile, polymorphism. chemical properties such are Hydrolysis, oxidation, reduction. Racemization polymerization. In this review we also studied about the biopharmaceutical Classification system ,in BCS we studied the Solubility and permeability profile for absorption of drug and also the rate of absorption of drug. This Review Also explain the different properties & technique for preformulation parameter evaluation parameter of drug.