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  Published Paper Details:

  Paper Title

A REVIEW ON SUPERDISINTEGRATING AGENT USED IN PHARMACEUTICAL FORMULATION

  Authors

  Disha P.Wankhede,  Damini A. Mundhare,  Laxmi S. Deshmukh,  Shravan S. Sawarkar,  Mohammad Tausif Shaikh Qayyum6

  Keywords

disintegranting agents, superdisintegrants, tablets, disintegration, dissolution

  Abstract


Disintegrating agents are super helpful in tablets. They help break up the compacted mass so the active ingredients can dissolve or release when in contact with fluids. The most important function of disintegrants is resist the ability of the tablet binder and bodily forces that act below compression to structure the tablet. Superdisintegrants provide rapid dissolution disintegration because of blended impact of swelling and water absorption. Superdisintegrants promotes the wettability and dispersibility of the machine, as a consequence increasing the disintegration and dissolution. One gram of superdisintegrants absorb 10-40 gm of water or liquid solution. After the absorption it produce pressure and leads to the entire tablet shape to break a side. Their particles are typically tiny and porous, which permit for fast tablet disintegration inside the mouth without an objectionable mouth-sense from either large particles or gelling. The debris are also compressible which enhance the tablet hardness and its friability. Powerful superdisintegrants offer advanced compressibility, compatibility and don't have any negative impact on the mechanical strength of formulations containing excessive-dose drug. Great disintegrating tablets are novel drug delivery system that dissolves, break into small particle's or dispersed the active pharmaceutical elements in saliva inside few seconds with or with out consumption of water. The quicker the dissolution of drug into the answer, quicker is the absorption and onset of medical effect

  IJCRT's Publication Details

  Unique Identification Number - IJCRT2310488

  Paper ID - 245337

  Page Number(s) - e357-e366

  Pubished in - Volume 11 | Issue 10 | October 2023

  DOI (Digital Object Identifier) -   

  Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882

  E-ISSN Number - 2320-2882

  Cite this article

  Disha P.Wankhede,  Damini A. Mundhare,  Laxmi S. Deshmukh,  Shravan S. Sawarkar,  Mohammad Tausif Shaikh Qayyum6,   "A REVIEW ON SUPERDISINTEGRATING AGENT USED IN PHARMACEUTICAL FORMULATION", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.11, Issue 10, pp.e357-e366, October 2023, Available at :http://www.ijcrt.org/papers/IJCRT2310488.pdf

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ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
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ISSN and 7.97 Impact Factor Details


ISSN
ISSN
ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
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