Published Paper Details:

ABSTRACT The main purpose of our garlic cream was to develop secondry treatment of skin infection, which enhances skin properties. That formulation agrees to a medicinal cream that has mainly two antifungal active properties. It helps to fungal treat fungal skin infection as well as other skin problems for any skin infection it is best topical approach and Best options. Because of the many advantages and conventional routes of drug administration, the development of topical drug delivery systems with systemic effects appears to be beneficial for a variety of medications. Garlic and clove oil was the active pharmaceutical ingredients (API) used to treat skin infections. It involves two types of primary and secondary emulsifiers, co-solvents, buffering agent, waxy material, two preservatives, a buffering agent, a humectants, and water in the cream base. When the active components are combined, they provide a potent antifungal effect. The many experiments were done to evaluate the physicochemical characteristics of formulated cream, such as visual inspection, pH measurement, expandability, skin irritant test, etc. The cream was further analyzed with the use of nutritional agar for antifungal activity. The medicated cream was good in consistency and color; however the smell of the garlic was quite unpleasant, so the odor of the garlic was masked with peppermint oil, which also acting as an additional antifungal agent, in improved version.