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ABSTRACT:- The medicinal herbs are the natures blessing for mankind to have healthy and disease free style of living. India is a unique nation of pharma culture in the universe where the medicinal plant included in the component of classical convention for complementing the quality of life. Parkinsonia aculeata plant that belonging to the family Fabaceae and it is a shrubby tree, which grows upto the height of 4-10 m. Presently Parkinsonia aculeata can be ground in most tropical, sub-tropical and Mediterranean countries. In this article pharmacological significance of Parkinsonia aculeata is precisely covered with different medicinal activities. The Phytoconstituent evaluation of the leaves, flowers, seeds and stems of Parkinsonia aculeata has exposed the presence of glycosides, flavonoids, alkaloids, saponins, tannins, phenolic compound, gums, and reducing sugars. Parkinsonia aculeata shows several health benefits because of the presence of a large number of bioactive phytochemicals. Habitually Parkinsonia aculeata is also known to the medicinal shrub for its beneficial effects as antimicrobial, anti cancer, anticonvulsant, analgesic, antipyretic and anti inflammatory, antidiabetic, antispermatogenic and antimalerial activities. A few plant species that have health-promoting effects and have been used as traditional foods and herbal remedies, though a limited information has been documented on their specific biological properties. Moreover, medicinal plants are low cost and tend to have fewer side effects than synthetic drugs. In this review, the introduction about plant, method of extraction of various parts of plants, bioactive constituents, pharmacological significance with result and discussion are succinctly explained.