Published Paper Details:

Objectives: To asses clinical features and metabolic disorders in PCOS; to find out relationship of PCOS with Infertility. Background: Polycystic ovarian syndrome (PCOS) is a common endocrine condition affecting women of reproductive age. It is characterized by chronic anovulation, hyperandrogenism and polycystic ovaries. Worldwide prevalence of PCOS ranges from 4% to 21%. Aims and objectives: The aim of this study was to determine prevalence of polycystic ovaries (PCO) and associated clinical and biochemical features among women with infertility attending gynaecological outpatient department (GOPD) at one government hospital and one private chamber in upazilla level, Bangladesh. Methods: Women with infertility attending from july 2021 to June 2022 were recruited to the study. Information on socio-demographic, obstetric, menstrual and other characteristics was collected. Clinical examination of acne, acanthosis nigricans and hirsutism, vaginal ultrasonography for PCO and biochemical analysis of luteinizing hormone (LH), follicle stimulating hormone (FSH), AMH, serum prolactin and testosterone were performed. Metabolic disorders were identified by measuring blood pressure, cholesterol level and Body Mass Index (BMI). Results: In this study it was found that 59% patients were obese among PCOS patients 90% were in ovulatory dysfunction. 66% PCOS patitents had hirsutism, 59% patients had acne, and 46% had impaired glucose tolerance. This study revealed that 41% PCOS patients had high TG level, 63% had LH: FSH more than 2 that was significant.