Published Paper Details:

Peptic Ulcer Disease is the ulceration of the gastrointestinal tract due to hyper acidity, resulting in mucosal erosion, acute pain and discomfort. Perforated Peptic Ulcer (PPU) is a life-threatening complication of peptic ulcer disease which is observed in around 2-14% of cases of peptic ulcer disease. A total of 100 patients were enrolled for study. Maximum incidence of ulcer perforation was seen in fourth decade. The ratio of male to female was approximately 12:1. Out of 100 patients, 92 patients were found to have pre-pyloric perforation while in 08 patients, the site of perforation was found to be in first part of duodenum. Fifty-five patients were positive for helicobacter pylori while 45 patients were tested negative. H.Pylori associated PUD is reported to be the commonest cause of morbidity and mortality, in especially LMIC nations. It is also one of the commonest abdominal emergency causing peritonitis. The outcome is multi-factorial depending on various factors like the underlying pathology, any co-morbid condition, the interval between perforation and treatment and the patient's age.