Published Paper Details:

This complex network has been organized in three sequential and overlapping steps. The first step of the inflammatory phase is an immediate response to injury; primary sensory neurons sense injury and send danger signals to the brain, to stop bleeding and start inflammation. The following target of the inflammatory phase, led by the peripheral blood mononuclear cells, is to eliminate the pathogens and clean the wound. Once this is completed, the inflammatory phase is resolved and homeostasis is restored. Phytochemical studies carried out on the Phragmites karka plants have demonstrated a wide variety of the biomolecules present in the plants which may be responsible for their use in traditional medicine. Through various bioassays, different biologically active compounds were identified. Since bioautography was used to monitor the wound healing activity of the extract, this shows that bioassays can be used as a guide during isolation. Although a p-coumaric acid compound isolated in this study was not identified due to a contaminant, this study shows that there is a biologically active compound belonging to the phenolic derivative. Which may be unique Further work is required to identify the specific phenolic and to determine if it is indeed unique and a good candidate for the treatment of infected wounds.