Published Paper Details:

The Validation are growing at a tremendous rate due to greater patient acceptability, multiple actions, increased potency, quicker relief and fewer side effects .The arena of pharmaceutical analysis calls for simple, rapid, accurate and specific methods of analysis which ensure the quality of the products. Form the analytical point of view, the drug present in a multi- component formulation suffer from severe spectral overlapping .The currently available methods for the analysis of multi-component formulations are different chromatographic techniques like HPLC. Although, these methods provide accurate and precise results, these suffer due to some drawbacks like time consuming nature, need expensive and solvents and the procedures are generally complex in nature. The aim of the present work is therefore to develop a simple, fast, convenient, economical, accurate and reliable method for the simultaneous determination of the formulations. Experimental designs, a fascinating area of chemo metrics are also applied in the chromatographic technique HPLC, proving the method is highly robust.