Published Paper Details:

For biological purposes, this study offers a simple method for synthesizing Tetrahydro Benzpyrimidine analogs. Further investigation into the unique properties of this novel family of antihypertensive medicines is required to further understand the molecular mechanism behind the activity seen. In order to improve the functionality of a number of molecules and learn more about the connection between structure and activity, a thorough examination is also required to find new physiochemical and biological traits. Some of the more recent antihypertensive substances that showed promise may be further developed to be more effective than the traditional drugs. The newly synthesized Tetrahydro Benzpyrimidine Heterocyclic Derivatives may therefore provide helpful leads for developing novel antihypertensive medications. The creation of Tetrahydro Benzpyrimidine derivatives that are more potent blood pressure reducers than currently existing derivatives is our aim. While having no impact on heart rate, these drugs significantly reduced the mean arterial blood pressure in rats. Additional pharmacological and toxicological studies are required to provide a comprehensive profile of these compounds for their prospective use in pharmaceutical therapy.