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Ayurveda is a science which treat the diseases both external and internal application of medicines in different form. In Bahaya Parimarjan, the medicine is administered for external use only. In Ayurveda, there are different form of external application are described for cure of various ailment. These different forms like Lepa, Udvartana, Malahara, Upnaha, Abhyanga etc. Description in topical or external application of the medicine in semi-solid form is Lepa. Lepa described in classics as the treatment of the various diseases and for beauty purpose. Preparation of Lepa is the medicament meant for topical application to the skin, coloring the hairs and others. In Lepa, wet medicinal drugs are made in paste form, if the drugs are in dry state then they are converted into paste form by adding little quantity of water and grinding. This paste is used as an external application and called as Lepa Kalpana. From Pharmaceutical point of view Lepa Kalpana is a form of Kalka Kalpana. Ayurvedic literature has not furnished complete details of Lepakalpana in a single chapter. Therefore one has to depend upon the scattered references to understand the concepts of Lepakalpana clearly. Acharya Charaka has described formulations for external application in 'Aragwadhiya Adhaya' but neither he himself nor commentator Chakrapani touched the various pharmaceutical aspects of Lepakalpana.