Published Paper Details:

After seeing rising cases of cancer soon it will become a global pandemic. Nowadays many therapies are available for the treatment of cancer which includes surgery, radiation therapy and chemotherapy. Many drugs are used in chemotherapy and doxorubicin is one of the most common drugs of chemotherapy for the last 50+ years. It is most commonly used for the treatment of solid tumors like breast, ovarian, bladder and thyroid and treatment of sarcomas like bone and soft tissue. It is also used in the treatment of acute lymphoblastic leukemia (ALL), acute myeloblastic leukemia (AML), Hodgkin lymphoma and small-cell lung cancers. Even though it can be used to treat some conditions, the drug doxorubicin is toxic to the majority of the body's major organs, notably the heart, which necessitates dose restriction. Additionally, doxorubicin promotes apoptosis and necrosis in normal tissue, leading to damage in the heart, liver, brain, and kidney. Toxicity can lead to congestive heart failure and gastrointestinal bleeding in some patients. Even though it can be used to treat some conditions, the drug doxorubicin is toxic to the majority of the body's major organs, notably the heart causing cardiotoxicity, which necessitates dose restriction. Additionally, doxorubicin promotes apoptosis and necrosis in normal tissue, leading to damage in the heart, liver, brain, and kidney. Toxicity can lead to congestive heart failure and gastrointestinal bleeding in some patients.