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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
Call For Paper - Volume 12 | Issue 7 | Month- July 2024
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Paper Title
PREFORMULATION STUDIES OF BUDESONIDE API: AN INTEGRAL PART OF FORMULATION DESIGN
Authors
Kompelli Rakesh, Sayyed Rajat
Keywords
Preformulation study, Budesonide, Solubility and Analytical methods
Abstract
Preformulation is defined as the study of the physical and chemical characteristics of pharmacological compounds both on their own and in combination with excipients. The primary step in the rational development of the dosage forms for the medicinal drug substance is preformulation research. Studying preformulation factors can help create pharmaceutical formulations that are dependable, safe, and effective. The aim of this study id to determine some of the physiochemical properties such as solubility, melting point, lambda max, infra-red spectra, etc. Budesonide is a glucocorticoid used in the treatment of asthma, inflammatory bowel disease, etc. The budesonide was studied for the various properties and the results for the organoleptic characteristics were found to be white crystalline powder. The melting point in average was found to be 228 oC. The solubility of budesonide in water was found to be low and was found to be higher in phosphate buffer pH 1.2.
IJCRT's Publication Details
Unique Identification Number - IJCRT2308262
Paper ID - 242465
Page Number(s) - c352-c359
Pubished in - Volume 11 | Issue 8 | August 2023
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Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Kompelli Rakesh, Sayyed Rajat, "PREFORMULATION STUDIES OF BUDESONIDE API: AN INTEGRAL PART OF FORMULATION DESIGN", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.11, Issue 8, pp.c352-c359, August 2023, Available at :http://www.ijcrt.org/papers/IJCRT2308262.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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