Published Paper Details:

There is a growing need for more patient-compliant dose forms in the current environment. The creation of mouth-dissolving tablets that quickly dissolve or disintegrate upon contact with the recipient's tongue or buccal mucosa is one significant advancement in this field. They have shown to be the best options for the elderly and paediatric populations, dysphagia patients, clinical circumstances when water intake is not possible, and medications with high first pass metabolism. The notion of higher patient compliance, quick absorption, rapid commencement of action, greater effectiveness, sufficient bioavailability to demonstrate needed pharmacological activity, and reduced toxicity are best suited by mouth-dispersing tablets (MDT). Brief information about ODTs, such as their definition, ideal and desired characteristics, advantages, limitations, and disadvantages is presented in this review. Other topics covered include drug candidates, formulation challenges, excipients with recent developments in super disintegrants, taste masking, manufacturing methods, evaluation criteria, and recent patents in ODTs.