Published Paper Details:

Hyaluronic acid is commonly known as hyaluronan or hyaluronate. Karl Mayer and John Palmer discovered hyaluronic acid in synovial fluid, the vitreous fluid of the eyes, the rooster's comb, the umbilical cord, and arterial walls. It is found in the bacterial cell walls of certain bacteria, like Streptococci and Staphylococci. They are the main commercial source of hyaluronic acid. It is naturally synthesis in 1934. Hyaluronic acid is found in connective tissue, synthesized by the protein named hyaluronan synthases, and it is destroyed by the enzyme named hyaluronidases. It plays a major role in different fields of medicine like, tissue engineering, cancer therapy, ophthalmology, osteoarthritis, and nerve reconstruction. It is used in skin regeneration, with an anti-ageing and moisturizing effect. Its applications are found in the pharmaceutical, cosmetic, and medical fields. Hyaluronic acid penetrates the skin due to its high molecular weight. The current study describes the main characteristics related to its use in cosmetology.