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Abstract: The current study has been appropriately powered and structured to estimate the prevalence of COPD and other comorbidities as well as to examine the distribution of COPD medication prescriptions. The main objective of this study?includes to determine the Demographic Characteristics, the Prevalence of COPD and its types, the distribution of COPD among Smokers and Non-Smokers, Evaluating the Clinical profile, Comorbidities Spirometric findings Radiographic profile ( Chest- X-ray), and Prescription pattern of drugs in the COPD patients. This study was conducted in the pulmonology department for 6 months. The total no.of cases during the study registered in the pulmonology department was 1500. Among 1500, 200 patients were having COPD. Among 200, 149 (75%) were males and 51 (25%) were females. This study indicated that the prevalence of COPD was more in males than females. The prevalence of COPD was found to be 13.3%. According to our findings, the prevalence of COPD was higher than the global prevalence, which ranges from 10.7% to 12.1%. COPD was more in the age group of 61 to 70. The most common symptoms observed in the patients were dyspnea, cough, expectoration, wheezing, fever, and chest tightness. The most common comorbidity observed in patients were Hypertension, diabetes, chronic liver disease, hypothyroidism, obesity, and ischemic heart disease, etc. patients were treated with multiple drugs including beta-2 agonists, antimuscarinics, inhaled corticosteroids, phosphodiesterase inhibitors, leukotriene receptor antagonists, antihistamines, antibiotics, systemic corticosteroids, oxygen therapy, and other drugs. prescribed antibiotics include amoxicillin, piperacillin, azithromycin, ceftriaxone, levofloxacin, and doxycycline.