Published Paper Details:

A Oral route is always considered as one of the best convenient route for administration of different pharmaceutical dosage form like solid dosage form such as capsule, tablet, pill and liquid dosage form such as syrup, elixir, emulsion and suspension. Fast Dissolving Drug Delivery system developed various fast disintegrating/dissolving formulations such as Mouth Dissolving Tablet's (MDT's) and Mouth Dissolving Film's. Mouth dissolving film is superior as compared to mouth dissolving tablet due to low cost of production. Mouth dissolving tablets are well established dosage forms available in the market. The numerous advantages that they offer to the patients (Geriatric and pediatric) in terms of compliance such patients are facing i.e difficulty in swallowing of tablet and capsule, the MDT's can bypass it, along with that it has other advantages like self-administration, rapid disintegration and faster dissolving in mouth without uptake of water offer rapid absorption hence rapid onset of action as compare to tablet, capsule, pill that make it versatile dosage form as well as to the manufacturers in terms of huge revenues by line extension of products are well known. In spite of such popularity, there seems to be lack of a standardized system to characterize these dosage forms. Enormous work has been done in this field, wherein some of the researchers have developed their own methods of preparation, taste masking and evaluation. This article attempts to present a detailed review regarding ideal properties, advantages, choice of excipient, mechanism of action of super disintegrant, characteristics, salient features, limitation, challenges and approaches for preparation of MDTs, patented technologies and technological advances made so far in the area of evaluation of mouth dissolving tablets with respect to special characteristics of these unique dosage forms.