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Aftimoon (CuscutareflexaRoxb.) is also known as Akashbel, Amarbel, and dodder plant in traditional medicine. India, Sri Lanka, Iran, Australia, Ceylon, and Malaya are all home to the plant. It belongs to the Convolvulaceae family and is an evergreen, perennial, rootless, leafless climber parasitic plant that is used to treat a variety of illnesses, including jaundice, gout, rheumatism, constipation, flatulence, chronic fever, and hiccups. Researchers are looking at the Cuscutareflexa's potential for having anticancer, antibacterial, antispasmodic, antihypertensive, hepatoprotective, antioxidant, haemodynamic, muscle relaxant, psychopharmacological, cardiotonic, and anticonvulsant properties, among others. A parasitic weed plant known as Cuscutareflexa has therapeutic properties and plays a significant role in Ayurveda. The therapeutic capabilities of Cuscutareflexa are dependent on its host plant since it grows over it and absorbs nutrients from it. Many compounds with medicinal potential and pharmacological and ethnomedical properties have been identified from this wonder plant. Phytochemical screening and gas chromatography-mass spectroscopy (GC-MS) methods were used to determine the phytochemical component of Cuscutareflexa (whole plant) chloroform and methanol extracts. In the plant sample, steroids, terpenoids, flavonoids, phenolic compounds, and cumarins were found through qualitative analysis. The parasite Roxb. twines and forms a tangled mass that covers the host plants. In Tamil, it is referred to as Akasvalli. The stem and seeds of this plant are extremely valuable medicinally. According to certain studies, the traditional societies and Indian tribes employed this plant as a purgative, a carminative, and an exterior treatment for skin conditions. For liver issues and constipation, stem decoction is utilized. Studies conducted in vitro demonstrated the antiviral and anticancer properties of the Cuscuta stem extract. To isolate and characterise the phytochemical ingredients with efficient pharmacological analysis, more research is required.