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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
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Published Paper Details:
Paper Title
A Review on A Journey of Sickle Cell Anemia : Breakthrough and Occurrence with Special Reference to India
Authors
Dr. Shuchita Chandorkar, Dr. Ranjana Verma, Dr. Shobha Shouche
Keywords
Key words: Sickle cell disease; RBCs; erythrocytes; HbS; polymerization.
Abstract
Abstract
Sickle cell disease is a genetic disorder in which RBCs of patient becomes sickle shaped, thereby decreasing oxygen carrying capacity. It is not necessarily expressed since birth but may appear in any age. It is caused by a gene that is heterozygous, it results in abnormal haemoglobin known as HbS. The polymerization of HbS alters both the structure and function of erythrocytes, initiating a cascade of events that ultimately affect a wide range of tissues. In India, the disease is found in many people who are unaware of it and usually remain untreated. Indian government is also running few programs to make people aware and proceed for treatment. The disease was first discovered in 1910, since then a sequence of studies has been done, and still going on to fight against the disease. The frequency of disease is more in people of tribal area in India, who belong to specific caste.
IJCRT's Publication Details
Unique Identification Number - IJCRT2303760
Paper ID - 233274
Page Number(s) - g496-g504
Pubished in - Volume 11 | Issue 3 | March 2023
DOI (Digital Object Identifier) - http://doi.one/10.1729/Journal.33801
Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Dr. Shuchita Chandorkar, Dr. Ranjana Verma, Dr. Shobha Shouche, "A Review on A Journey of Sickle Cell Anemia : Breakthrough and Occurrence with Special Reference to India", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.11, Issue 3, pp.g496-g504, March 2023, Available at :http://www.ijcrt.org/papers/IJCRT2303760.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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