Published Paper Details:

Today, there is a lot of interest in the use of the nasal route for the delivery of difficult-to-deliver medications including tiny polar compounds, vaccines, hormones, peptides, and proteins. The nasal cavity is ideally suited for systemic drug delivery because of its high permeability, high vasculature, low enzymatic environment, and avoidance of hepatic first pass metabolism. Due to the need for quick and/or precise therapeutic targeting of the brain, numerous drug delivery methods for nasal application of liquid, semisolid, and solid formulation are being researched. These disorders include Parkinson's disease and Alzheimer's disease. The distribution of biotechnological products such proteins, peptides, hormones, and DNA plasmids for DNA vaccines to provide increased bioavailability is ideally suited for it. . This study aims to cover various aspects of nasal absorption, bioavailability barriers, techniques to enhance nasal absorption, current advancements in nasal dosage form design, and applications of nasal drug delivery system.