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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
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Paper Title
ANTIOXIDANT SYLIMARIN IS THE LEVER BETWEEN LIVER AND HOMEOSTASIS FROM HERBAL SOURCE
Authors
Pruthviraj Karshanbhai Chaudhary, Zeelkumar Kirtibhai Chaudhari, Soumya Chakraborty, Vedansh Upadhyay, Dr Dhrubo Jyoti Sen
Keywords
Silybum marianum, Hepatoprotector, Lipoperoxidation, Silymarin
Abstract
Silymarin is a natural compound derived from the species Silybum marianum, which is commonly known as Milk thistle. This plant contains at least seven flavoligands and the flavonoid taxifolin. The hepatoprotective and antioxidant activity of silymarin is caused by its ability to inhibit the free radicals that are produced from the metabolism of toxic substances such as ethanol, acetaminophen, and carbon tetrachloride. The generation of free radicals is known to damage cellular membranes and cause lipoperoxidation. Silymarin enhances hepatic glutathione and may contribute to the antioxidant defense of the liver. It has also been shown that silymarin increases protein synthesis in hepatocytes by stimulating RNA polymerase I activity. A previous study on humans reported that silymarin treatment caused a slight increase in the survival of patients with cirrhotic alcoholism compared with untreated controls.
IJCRT's Publication Details
Unique Identification Number - IJCRT2303536
Paper ID - 232785
Page Number(s) - e734-e742
Pubished in - Volume 11 | Issue 3 | March 2023
DOI (Digital Object Identifier) -
Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Pruthviraj Karshanbhai Chaudhary, Zeelkumar Kirtibhai Chaudhari, Soumya Chakraborty, Vedansh Upadhyay, Dr Dhrubo Jyoti Sen, "ANTIOXIDANT SYLIMARIN IS THE LEVER BETWEEN LIVER AND HOMEOSTASIS FROM HERBAL SOURCE", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.11, Issue 3, pp.e734-e742, March 2023, Available at :http://www.ijcrt.org/papers/IJCRT2303536.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
ISSN and 7.97 Impact Factor Details
ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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