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  Published Paper Details:

  Paper Title

DESIGN AND EVALUTION OF ORAL DISPERSIBLE TABLET OF MODEL DRUG CONTAINING HYDROCORTISONE FUMRATE

  Authors

  Nandakishor B. Deshmukh,  Nilesh P. Tekade,  Bhaskar S Ambhore,  Shubhada V Bhopale,  Shubham V Jadhav

  Keywords

Oral Dispersible Tablet , Hydrocortisone Fumrate

  Abstract


Oral Dispersible Tablets Are Patient Friendly Dosage Form That Rapidly Disintegrate Or Dispersed In Mouth Without The Need Of Water. Oral dispersible tablet of Hydrocortisone was develop in present study to get rapid onset of action to increase bioavailability and to increase patient compliance In The Present Investigation Ten ODT Formulations Of Hydrocortisone its is used Arthritis, Blood ,Hormone ,Immune System Disorders, Skin And Eye Conditions, Breathing Problems And Severe Allergies.Were Prepared different formulation by Using Different Superdisintegrants like Sodium Starch Glycolate , Crospovidone Cross Carmellose,Sodium Microcrystalline Cellulose , Aspartame, Magnesium Stearate , Talc , Aerosil Pineapple Flavour Mannitol By Direct Compression Method. The Effects Of Different Concentration On The Release Profile Of Hydrocortisone ODT Were Studied. Developed ODT Were Studied For Their Physicochemical Properties And In Vitro Drug Release Profile. The Studied Parameters Were Found To Be Satisfactory For All ODT Formulations Of Hydrocortisone Disintegration Time For All The Formulations Was Found To Be Less Than 30 Seconds. Disintegration Time For All ODT Decreased With Increase In Disintegrant Concentration. The aim of study is to develop and evaluate the oral dispersible tablets of Hydrocortisone To improve patient compliance,develop cost effective product. and enhanced the onset of action of Hydrocortisone also enhance the safety and efficacy of Hydrocortisone.

  IJCRT's Publication Details

  Unique Identification Number - IJCRT2303459

  Paper ID - 232733

  Page Number(s) - e69-e87

  Pubished in - Volume 11 | Issue 3 | March 2023

  DOI (Digital Object Identifier) -   

  Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882

  E-ISSN Number - 2320-2882

  Cite this article

  Nandakishor B. Deshmukh,  Nilesh P. Tekade,  Bhaskar S Ambhore,  Shubhada V Bhopale,  Shubham V Jadhav,   "DESIGN AND EVALUTION OF ORAL DISPERSIBLE TABLET OF MODEL DRUG CONTAINING HYDROCORTISONE FUMRATE", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.11, Issue 3, pp.e69-e87, March 2023, Available at :http://www.ijcrt.org/papers/IJCRT2303459.pdf

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ISSN: 2320-2882
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Journal Starting Year (ESTD) : 2013
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ISSN and 7.97 Impact Factor Details


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ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
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