Published Paper Details:

Among all breast cancer subtypes, triple-negative breast cancer (TNBC) has the worst outcomes. It is likely to recur and metastasize. Due to a lack of expression of the canonical molecular targets, conventional chemotherapeutic agents, radiotherapy and surgery have been the only options for treating this cancer. The phytochemicals derived from natural compounds have shown very significant inhibitory effects on TNBC. The advantages of natural compounds include lower toxicity, minimal side effects, and ease of accessibility. There is evidence that secondary metabolites found in natural products can inhibit TNBC. These include alkaloids, terpenoids, steroids, flavonoids, and flavonols. They may also help uncover new cancer-fighting strategies through their compositions. A review of this study may be able to help us understand how natural substances and medicinal herbs can decrease specific tumor types. Moreover, it will contribute to the development of new and highly efficient antitumor therapies for TNBC.