Published Paper Details:

Simple, rapid, economical, precise and accurate Stability indicating RP- HPLC method for the estimation of Dapagliflozin Propanediol Monohydrate and Teneligliptin in Tablet Dosage Form has been developed. A reverse phase high performance liquid chromatographic method was developed for the estimation of Dapagliflozin Propanediol Monohydrate and Teneligliptin in Tablet Dosage FORM has been developed. The separation was achieved Column Kromasil C18 (150 x 4.6) 5 �m ID, Gradient program0.1%TFA: Methanol, as mobile phase, at a flow rate of 1 ml/min. Detection was carried out at 235 nm retention time of DAPA and TENE was found to be 9.47and 3.61 min. The method has been validated for linearity, accuracy and precision. Linearity observed for Dapagliflozin Propanediol Monohydrate and Teneligliptin 49.94-298.24 ?g/ml. Developed method was found to be accurate, precise and rapid for estimation of Dapagliflozin Propanediol Monohydrate and Teneligliptin in Tablet Dosage Form. The drug was subjected to stress condition of hydrolysis, oxidation, photolysis and Thermal degradation, under same chromatographic condition. The stress samples were assayed on RP-HPLC system.