Published Paper Details:

Tablets intended for buccal membrane delivery that are mucoadhesive are unusual formulations with a number of technological advantages. However, the statistics used in its formulation are not standardised. This article's objective is to assess the data pertaining to the final quality of this technology through a scientific study and meta-analysis. Using a direct compression technique, buccal tablets were made using mucoadhesive polymers such chitosan, HPMC K4M, Na CMC, and soda alginate. Numerous metrics, including hardness, weight uniformity, thickness, percent friability, swelling index, mucoadhesive strength, surface pH, drug-excipient interaction research, drug content uniformity, and in vitro drug release study, were used to describe buccal tablets. Low bioavailability and significant drug depletion from the indefinite quantity type are the results of continual salivation and the swallowing that follows. Therefore, different transmucosal routes like nasal, rectal, vaginal, ocular and oral mucosae are being thought of as alternatives typical to standard to traditional} oral indefinite quantity forms for drug delivery to avoid the on top of disadvantages related to conventional oral delivery (i.e., tablets, capsules, syrups, etc.). of those routes of delivery, the buccal oral membrane has emerged in concert of the target sites for administration of medicine in an exceedingly large choice of indefinite quantity forms, particularly for those drugs targeted for local delivery in the oral cavity and systemic absorption. This review describes the structure of mucosal layer, mechanism of action of mucoadhesion, and evaluation parameters of tablets.