Published Paper Details:

Preformulation may be a cluster of studies that specialise in the physicochemical properties of a drug candidate that would have an effect on the drug performance and also the development of an indefinite quantity kind. This could offer necessary data for formulation style or support the need for molecular modification. Each drug has own intrinsic chemical and physical properties that has been take into account before development of pharmaceutical formulation. This property provides the framework for medication combination with pharmaceutical ingredients within the fabrication of indefinite quantity kind. Objective of preformulation study is to develop the elegant, stable, effective and safe indefinite quantity kind by establishing kinetic rate profile, compatibility with the opposite ingredients and establish Physico-chemical parameter of drug substances. Among these properties, drug solubility, partition coefficient, dissolution rate, polymorphic forms and stability are plays important role in preformulation study.