Published Paper Details:

HIV still poses a serious hazard to public health, and co-infection with Hepatitis B and/or C virus adds another element of danger. When compared to a single/mono infection, this double/triple infection increases morbidity and mortality. Hence, the regular checking for HBV and HCV infections in People with HIV (PWH) will be helpful in proper patient care and management. To study the prevalence of HBV and HCV coinfection among PWH and people without HIV (Non-PWH). A total of 220 cases with HIV (n=110) and without HIV (n=110) infection were included in the study. Samples were tested for HBV and HCV infection by Enzyme Linked Immunosorbent Assay (ELISA) method. Odds ratios, 95% confidence interval was calculated and the relative risk factors were analysed. Among the 110 PWH, 4 patients shown, HIV-HBV co-infection (Odds ratio (OR):2.0377 with 95% Confidence Interval (CI): 0.3655 to 11.3620) and in 5 patients, HIV-HCV co-infection (OR: 5.190 with 95% CI: 0.5964 to 45.1758 was observed. In 110 Non-PWH, 2 were HIV-HBV co-infected (1.81%) and 1 was HIV-HCV co-infected (0.90%). None of the participant either from PWH or from Non-PWH is positive for Triple co-infection of HIV-HBV-HCV. Our study demonstrates the co infection of HBV and/or HCV in HIV patients that significantly associated with immunodeficiency. The prevalence of HIV-HCV co-infection is more than HIV-HBV con-infection. But the prevalence of HBV is more in non-PWH than HCV. These findings emphasis the necessity of improving integrated care approaches, especially for the population with immunodeficiency, in order to lower the risk of viral transmission.