Published Paper Details:

Solubility is the process of soluble solids in a liquid phase to give the same system. Solubility is one of the most important parameters for achieving the desired concentration of a drug in the distribution system to reflect the drug response. Water-soluble drugs usually require high doses to achieve plasma concentration after treatment orally. Low-melting aqueous melting is a major problem encountered with the construction of new chemical enterprises. Any medicine to be absorbed should be present in the form of an aqueous solution in the place of absorption. Water is the solvent of choice in the manufacture of pharmaceutical liquids. Most drugs have a weak acid and a poor foundation water melting. Therefore various methods are used to improve the solubility of soluble drugs including micronization, chemical modification, preparation, solid dispersion, compaction, mixing, micellar solubilization, hydrotropy etc. The purpose of this review article is to explain solubilizaton techniques for effective absorption and improved bioavailability