Published Paper Details:

COVID19 is caused by the virus that affects the respiratory system leading to difficulty in breathing, head ache, loss of smell and taste, fever, dry cough, fatigue to the affected person. It also infects the healthy individual through the droplets of infected person. No antiviral agents are effective against COVID 19. During first and second wave of COVID 19 Antivirals such as Ivermectin, Remdesivir, Ritonavir, Lopinavir and Antimalarials such as Hydroxychloroquine was administrated for number of patients who are suffering with COVID 19 but these drugs does not decrease the replication of SARS COV virus and no relief to the patients from the symptoms and no decrease in mortality rate after use of Antivirals and Antimalarials. Still, clinical trails are going on for certain medications such as Janus kinase Inhibitors, Monoclonal antibodies, IL 6 inhibitors, Steroids which are recommended by WHO and drug (oral pills) Paxlovid, Molnupiravir (presently reviewed by Health Science Authority) which was authorised by US FDA. This review article contains the Medications, Mechanism of action, Dose, Dosage form, Frequency, Drug interaction of Paxlovid, Contraindications and Use of drugs based on severity of infection and Information on clinical trials of paxlovid. No antiviral agents are effective against COVID 19.