Published Paper Details:

Clinical features resembling those of diabetes mellitus were described by the ancient Egyptians 3,000 years ago. The term "diabetes" was first coined by Araetus of Cappodocia (AD 81-133). Later Thomas added the word mellitus (honey sweet). Willis (Britain) in 1675 after rediscovering the sweetness of patients' urine and blood (first observed by ancient Indians). It was not until 1776 that Dobson (Great Britain) first confirmed the presence of excess sugar in the urine and blood as the cause of In modern times, the history of diabetes coincided with the rise of experimental medicine. An important milestone in the history of diabetes is the establishment of the liver's role in glycogenesis and the concept that diabetes results from excess glucose production. Claude Bernard (France) in 1857. The role of the pancreas in the pathogenesis of diabetes was discovered by Mering and Minkowski (Austria) in 1889. This discovery later formed the basis for the isolation and clinical use of insulin by Banting and Best (Canada) in 1921. Attempts to create an orally administered hypoglycemic agent ended successfully with the first commercialization of Tolbutamide and Carbutamide in 1955 This report also provides an overview of the history of dietary control and the acute and chronic complications