Published Paper Details:

Transdermal patches deliver the drug through the skin in a controlled and predetermined manner in order to increase the therapeutic efficacy of drug and reduces side effect of drug. Triptan that has a favorable tolerability profile and patients have reported greater satisfaction are used in form of patches. It delivers the drug through skin portal to systemic circulation at a predetermined rate over a prolonged period with a fixed amount of dose. Use of the methods outlined in this review in choosing a triptan for an individual patient is probably more likely to get to migraine relief than making an educated guess as to which triptan is most appropriate. There are two non-oral delivery systems nowadays available in the United States for the mild treatment of migraine: three nasal sprays and two injectable formulations. Even though nasal sprays depend partially on nasal mucosal absorption, a significant amount of drug is consumed, transits the stomach and is absorbed in the small intestine, which is not as fast or effective a route of delivery for those migraineurs with gastric stasis.