Published Paper Details:

With the antibiotic resistance growth, there is rise of interest in discovering novel antimicrobial agents. The antibiotics restored with metal nanoparticles because of its enduring antibacterial properties. This investigation aimed for gold nanoparticles biosynthesis and determines the antibacterial efficacy against some human bacterial species.The gold nanoparticles was characterized by UV, FT-IR and DLS. The impacts of synthesized gold nanoparticles were tested against E.coli (Gram-negative), S. aureus (Gram positive), S.pneumoniae (Gram positive) and K. pneumonia (Gram-negative) by disc diffusion method (Kirby Bauer test).The gold nanoparticles were synthesized from the plant Coleus amboinicus leaves extract. The spectrum of UV-Vis revealed a higher peak at 546 nm; the FTIR showed the phenolic compounds in the plant extract that were responsible for the formation of gold nanoparticles and the DLS revealed the size to be 104.5 nm. The gold nanoparticles indicate the minimum and maximum activity for antibacterial pathogens towards E.coli, K. pneumonia, S.pneumoniae and S. aureus. Thus, the synthesized gold nanoparticles might be a better option to develop an antibacterial agent against selected bacterial human pathogens.