Published Paper Details:

Stretch marks (Striae distensae) are visible lines on the outer skin located usually on abdomen,breats,thighs.Stretch marks which develop on pregnant women known as striae gravidarum. Almost 50-90% of pregnant women may develop striae distensae.It is caused due to sudden increase in weight during pregnancy,due to rapid weight gain the collagen fibres present between dermis and epidermis layer of skin gets break down and stretch marks appears.Because of various side effects of synthetic medications,the use of herbal medications has increased. To avoid side effects,oil obtained from the leaves of Centella asiatica linn i.e Gotukola(GKO) was incorporated into the formulation stimulates collagen synthesis by energizing dermal fibroblast. The main active ingradient found in gotukola is triterpenoids (saponins) which includes asiaticosides,it increase collagen production in the body this may help to prevent new stretch marks from forming as well as help to heal any existing marks.The objective of the present study was to formulate and evaluate derma stick for the management of striae gravidarum. Derma stick which are rarely available in the market for the treatment of stretch marks , it avoids the use of fingertip.Derma stick was prepared by heating and congealing method by changing the concentration of butters.Total 7 formulations were prepared among these F7 batch,i.e,SBMBCB (shea butter,mango butter and cocoa butter) was selected as an optimized batch ,In this (4.6%) concentration of oil was added.The final formulation batch GKOSBMBCB shows pH (6.4),Breaking point(120 gm),No skin irritancy ,better spreadability and consistency, hence this batch containing gotukola oil can be used as an appropriate formulation to treat striae gravidarum.