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  Published Paper Details:

  Paper Title

EFFECT OF BAUHINIA ACUMINATA-L STEM BARK EXTRACT ON DETOXIFICATION OF ARSENIC IN RATS

  Authors

  Amartya De,  Susanta Kumar Bandyopadhyay,  Tapan Kumar Mandal

  Keywords

Arsenic, Rats, Bauhinia acuminata, speciation, total arsenic concentration.

  Abstract


A study was undertaken to evaluate the efficacy of Bauhinia accuminata (BA) stem bark extract against sodium arsenite (NaAsO2) induced toxicity in adult albino rats. Forty eight adult albino rats having body weight 150-200 gm of either sex were randomly divided into four groups, viz., A0, A1, A2 and A3 each contains twelve rats.Sodium arsenite was administered at 4mg/kg daily in drinking water for 90 days to groups A1, A2 and A3. Groups A2 and A3 were orally treated with BA stem bark extract at 300 mg/kg (1/10th of LD50) and at 150mg/kg (1/20th of LD50) daily respectively from day 91 to 120 day, while only water was given to group A0 (control). Tissue samples, hair, faeces were collected at different days for analysis of total arsenic concentration. Speciation was performed on faeces, liver and hair. The results expresses that the stem bark extract of Bauhinia acuminata (BA) may be effective against induced arsenicosis in rats.

  IJCRT's Publication Details

  Unique Identification Number - IJCRT2207178

  Paper ID - 223091

  Page Number(s) - b386-b391

  Pubished in - Volume 10 | Issue 7 | July 2022

  DOI (Digital Object Identifier) -   

  Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882

  E-ISSN Number - 2320-2882

  Cite this article

  Amartya De,  Susanta Kumar Bandyopadhyay,  Tapan Kumar Mandal,   "EFFECT OF BAUHINIA ACUMINATA-L STEM BARK EXTRACT ON DETOXIFICATION OF ARSENIC IN RATS", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.10, Issue 7, pp.b386-b391, July 2022, Available at :http://www.ijcrt.org/papers/IJCRT2207178.pdf

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ISSN: 2320-2882
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Journal Starting Year (ESTD) : 2013
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ISSN and 7.97 Impact Factor Details


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ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
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