Published Paper Details:

Transdermal drug delivery systems were developed as interesting research and one of the most regularly developed pharmaceutical goods on the global market in the field of pharmaceutical technology. Other delivery modes, like oral and intravenous, have limitations that this approach can solve. Nanocarriers, niosomes, electrosomes, liposomes, proniosomes, ethosomes, and transferosomes are vesicular targeted carriers for drug delivery. Niosomes and proniosomes, for example, are regarded to be improved carriers for increasing therapeutic efficacy and bioavailability while lowering side effects, making them a viable transdermal drug delivery system. Both are amphiphilic non-ionic surfactant-based vesicles. Niosomes are formed when non-ionic surfactant vesicles assemble. The type of nonionic surfactant employed, the method of production, the hydration temperature, and other variables all influence niosome formation. In this review paper, we sought to incorporate all of the basic data about niosomes, including different techniques of manufacture, distinct types of niosomes, factors impacting their production, and so on. Niosome toxicity is a term used to describe the toxicity of niosomes. Transdermal drug-delivery penetration enhancers, Mechanism of action of niosomes, and recent advances in the domain of niosomal research. The niosome's role as a pharmacological carrier in the skin is also highlighted.