Published Paper Details:

Diabetes mellitus and thyroid disorders are the most common endocrinopathies. Thyroid disorders are pathological states that can adversely affect glycemic control in diabetics and has the potential to affect their health. Hypothyroidism is found commonly in diabetes and is associated with advanced age, particularly in type 2 diabetes. The current study was a Comparative Cross-sectional and hospital-based study which was undertaken in the Outpatients and Inpatient Department of NMCTH, Birgunj, Parsa, Madhesh Province, Nepal. The study variables for the study were Fasting Blood sugar, postprandial blood sugar, HbA1C, fT3, fT4, TSH, Age, and Gender. We had enrolled two hundred and fifty participants, out of which 60% were male and 40% were female participants. In our population the pattern of thyroid status showed that euthyroidism predominated contributing 64.8%, followed by subclinical hypothyroidism (24%) and then primary hypothyroidism (11.2%). There was significant positive correlation with FBS, PPBS, HbA1C and TSH having correlation coefficient (0.23, 0.00), (0.20, 0.00), (0.16, 0.00) and (0.67, 0.00) respectively. There was a significant negative correlation with fT3 and fT4 having correlation coefficients (-0.32, 0.00) and (-0.28, 0.00) respectively. Our study revealed that subclinical and primary hypothyroidism may occur in the diabetic population. Once the diabetes is diagnosed the patients should be screened for the thyroid profile to diagnose the thyroid abnormalities mainly hypothyroidism. Diabetes mellitus and thyroid disorders are the most common endocrinopathies. Thyroid disorders are pathological states that can adversely affect glycemic control in diabetics and has the potential to affect their health. Hypothyroidism is found commonly in diabetes and is associated with advanced age, particularly in type 2 diabetes. The current study was a Comparative Cross-sectional and hospital-based study which was undertaken in the Outpatients and Inpatient Department of NMCTH, Birgunj, Parsa, Madhesh Province, Nepal. The study variables for the study were Fasting Blood sugar, postprandial blood sugar, HbA1C, fT3, fT4, TSH, Age, and Gender. We had enrolled two hundred and fifty participants, out of which 60% were male and 40% were female participants. In our population the pattern of thyroid status showed that euthyroidism predominated contributing 64.8%, followed by subclinical hypothyroidism (24%) and then primary hypothyroidism (11.2%). There was significant positive correlation with FBS, PPBS, HbA1C and TSH having correlation coefficient (0.23, 0.00), (0.20, 0.00), (0.16, 0.00) and (0.67, 0.00) respectively. There was a significant negative correlation with fT3 and fT4 having correlation coefficients (-0.32, 0.00) and (-0.28, 0.00) respectively. Our study revealed that subclinical and primary hypothyroidism may occur in the diabetic population. Once the diabetes is diagnosed the patients should be screened for the thyroid profile to diagnose the thyroid abnormalities mainly hypothyroidism.