Published Paper Details:

When a self-forming encapsulated lipid bi-layer was hydrated, liposomes or lipid vesicles were discovered; liposome drug delivery systems have played a significant role in the creation of useful medications to improve therapies. Liposome formulations have recently been optimized to reduce toxicity while enhancing target site accumulation. The suppression of rapid liposome clearance by regulating particle size, charge, and surface hydration is one of several new liposome manufacturing methods based on lipid drug interaction and liposome disposition mechanism. Targeting tissue with or without the expression of target recognition molecules on the lipid membrane is the most common therapeutic application of liposomal drug delivery. Physical, chemical, and biological factors are used to characterize the liposomes. Liposome size is another important metric that aids in the identification of the liposome, which is normally accomplished by sequential extrusion at low pressure through a polycarbonate membrane (PCM). Antiviral, antifungal, antimicrobial, vaccines, anti-tubercular medicines, and gene treatments can all benefit from this route of drug delivery since it improves safety and efficacy. Liposomes are being used in immunology, dermatology, vaccine adjuvant, eye diseases, brain targeting, infectious disease, and tumor therapy, among other fields. The specific binding properties of a drug-carrying liposome to a target cell such as a tumor cell and specific molecules in the body (antibodies, proteins, peptides, and so on); stealth liposomes, which are especially being used as carriers for hydrophilic (water soluble) anticancer drugs like doxorubicin and mitoxantrone; and bisphos-phonate-liposome mediated macrophage depletion are some of the Researchers working in the field of liposomal medication delivery will benefit from this review.