Published Paper Details:

Historically, plants have shown great promise in the treatment of diseases and have been a source of inspiration for novel drug compounds. There has been considerable public and scientific interest in the use of phytochemicals derived from dietary components to combat human diseases. Turmeric (Curcuma longa L.) is the shining star among the cornucopia of traditional medicinal plants. Since 1970, when curcumin first attracted the interest of scientific medical researchers, studies have reported its suppressive effects on various medical conditions, including high serum cholesterol levels, free radical damage to tissues, diabetic cataracts, diabetic damage to pancreatic insulin-producing cells, diabetic wounds, rheumatoid arthritis, inflammatory bowel disease, Crohn's disease, psoriasis, cancer, atherosclerosis, inherited peripheral neuropathies, liver damage caused by chemicals and drugs, and microbial infections. Curcumin also shows especially exciting prospects for the treatment of Alzheimer's disease, Parkinson's disease, and cystic fibrosis. The main aim of this work is to conduct phytochemical screening for the presence of major secondary metabolites, physicochemical parameters, and curcumin content in turmeric. Using a combination of solvent extraction, chromatography, and spectroscopic techniques, we systematically separated and identified the total curcuminoids and turmerones from turmeric root. The extraction was optimized for maximum yield and purity. The isolated curcuminoids, primarily consisting of curcumin, demethoxycurcumin, and bisdemethoxycurcumin, were quantified using High-Performance Liquid Chromatography (HPLC). Turmerones, including ar-turmerone, ?-turmerone, and ?-turmerone, were isolated and identified through Gas Chromatography-Mass Spectrometry (GC-MS). The results highlight the efficiency of the applied methods and provide a robust approach for the extraction of these valuable bioactive compounds. This study not only contributes to the understanding of turmeric's phytochemical profile but also supports its potential therapeutic applications in pharmaceuticals and nutraceuticals.