Published Paper Details:

Background : Opioid Free Anesthesia (OFA) is an anesthetic technique that avoids intraoperative opioids to minimize side effects of opioids, reduce the need for postoperative opioids and produce better postoperative outcomes. This study aims to analyze the comparison of the side of OFA and opioid anesthesia (OA) in elective surgery patients at Dr. Hospital Soetomo Method : This study is an experimental study with Single Blind randomized involving adult patients undergoing elective surgery from May 2021 to August 2021 under general anesthesia for airway management intubation at RSUD DR. Soetomo. Side observed were Wong Baker Face Scale (WBFS), incidence of hypoxia, ileus, delirium and postoperative nausea and vomiting. Results: 60 samples obtained 30 subjects in the control group and 30 people in the treatment group with 23 male and 37 female. Evaluation of postoperative pain found 5 subjects with moderate-severe WBFS scale in the control group and 3 subjects in the treatment group (0.706); and significant differences in the incidence of hypoxia (9 subjects in the control group and 2 subjects with hypoxia (p = 0.020); ileus in the form of 14 subjects in the control group and 2 subjects in the treatment group (p = 0.002); the incidence of delirium (p = 0.026) in the form of 8 subjects in the control group. and 1 subject in the treatment group, and the incidence of nausea and vomiting (p=0.012) in 14 subjects in the control group while 5 subjects in the treatment group. Conclusion: Both groups received adequate analgesics so that they had similar WBFS, but the incidence of side was significantly different in the two groups where the incidence of hypoxia, ileus, delirium, and postoperative nausea and vomiting are lower. So that OFA could be considered as an anesthetic technique of choice.