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  Published Paper Details:

  Paper Title

DEVELOPMENT & EVALUATION OF ANTIMICROBIAL HERBAL OINTMENT OF ROOTS OF CASSIA ALATA. LINN

  Authors

  Rehapade V,  Mujariya R

  Keywords

Cassia alata, antibacterial properties, Bacillus subtilis, Staphylococcus aureus; Escherichia coli, Pseudomonas aeruginosa, herbal ointments.

  Abstract


In this study, the antibacterial potency of herbal ointments formulated with methanolic extract of Cassia alata was evaluated. The preliminary in vitro antibacterial activity of the methanolic extracts of sun-dried leaves of Cassia alata was determined against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa using the Agar cup plate method. The antibacterial activity of the extract was predominantly against Gram-positive organisms. Herbal ointments were prepared by incorporating the methanolic extract of Cassia alata (10 % w/w) into aqueous cream, emulsifying ointment and simple ointment bases and evaluated for their in vitro antibacterial efficacy. The formulation containing Cassia alata extract in aqueous cream showed comparatively better antibacterial activity than the other formulations in the following order: aqueous cream > emulsifying ointment > simple ointment > crude extract. The herbal ointment also compared favourably with a commercial brand of Gentamicin ointment. This study shows that Cassia alata has antibacterial activity and also has high potential as antibacterial agent when formulated as ointment for topical use and could therefore explain the successes claimed in the folk use of the plant in the treatment of common skin conditions.

  IJCRT's Publication Details

  Unique Identification Number - IJCRT2110097

  Paper ID - 212320

  Page Number(s) - a788-a798

  Pubished in - Volume 9 | Issue 10 | October 2021

  DOI (Digital Object Identifier) -    http://doi.one/10.1729/Journal.28300

  Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882

  E-ISSN Number - 2320-2882

  Cite this article

  Rehapade V,  Mujariya R,   "DEVELOPMENT & EVALUATION OF ANTIMICROBIAL HERBAL OINTMENT OF ROOTS OF CASSIA ALATA. LINN", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.9, Issue 10, pp.a788-a798, October 2021, Available at :http://www.ijcrt.org/papers/IJCRT2110097.pdf

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ISSN: 2320-2882
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Journal Starting Year (ESTD) : 2013
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ISSN and 7.97 Impact Factor Details


ISSN
ISSN
ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
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