Published Paper Details:

Background: Infertility in females is a complex global health problem. It has multiple socio-cultural consequences which are usually associated with thyroid and prolactin hormone disorders. Hence it has become a clinical challenge to endocrinologist and gynaecologist. Method: Out 300, 150 primary infertile and group A and 150 secondary infertile group B women were studied. Blood examination included complete haemogram ESR, hormonal assay. Radiologically USG perineum and abdomen; chest-x-ray was studied. Results: Prolactin hormone levels 0-20 ng/ml was highest in secondary infertility (group-B) 98 (65.3%), 21-100 ng/ml was highest in group-A, >100 ng/ml was observed only in group-B i.e. 4 (2.6%), Regular Menses were highest in group-A 47 (31.3%), Oligomenorrhea was also highest in group-A 70 (46.6%), while Amenorrhea was highest in group-B 32 (21.3%), Menorragia was highest in group-A 12 (8%), Duration of marriage period was highest in group-B (secondary infertile). Conclusion: Hyper prolactenemia with thyroid dysfunction are the major contributor of hormonal factors in primary and secondary infertility of women. Hence estimation of prolactin and TSH levels might be considered as essential assessment of patients with fertility disorders.