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Urticaria is a disease, which is characterized with development of angioedema or wheals or both. It has three types, chronic spontaneous urticaria, acute spontaneous urticaria and chronic inducible urticaria. In most of the cases of urticaria, oedema spread on upper surface area of skin which is causes due to increase in capillary permeability. Whereas certain body cites like as lips and hands, the oedema spread deeper. It is associated with angioedema of lips, face, throat and rarely wheezing, abdominal pain. In cases of severe angioedema it can be life-threatening because it will cause respiratory obstruction, it is rare condition. This disease commonly affect young adult rather than old age group, female are more affected then male. Approximately 15 to 20% of population will suffer from urticaria, once during their life time. In alternative medicine, we use some medication like as Fexofenadine, cetrizine and levocetrizine are the first line of treatment; this treatment of urticaria is symptomatically which is non curative method. This alternative medicine method not eliminates the recurrence tendency of urticaria. Whereas, In homoeopathy we treat a patient on the basis of individualization this method reduce the chances of recurrence significantly. Homoeopathic literature acknowledges many medicines for the Urticarial condition, of which a similimum can help a patient for keeping the disease at bay for a longer period. Homoeopathic remedies can offer gentle and safe relief.