Published Paper Details:

Abstract: Background: Stomal recurrence means a recurrence experienced by patients with laryngeal carcinoma after total laryngectomy with a high mortality rate. It is essential to identify the risk factors to predict stomal recurrence. However, factors contributing to stomal recurrence indicate controversial results. Tumor expansion, thyroid nodules, and free margins become the risk factors that are easily identified. The objective: This study aims to describe the correlation between tumor expansion, thyroid nodules, and free margins with stomal recurrence after total laryngectomy. Methods: This study applied an analytical observational study with retrospective cohort studies by employing secondary data. The samples included patients who had experienced a total laryngectomy from January 1, 2015, to December 31, 2019, and those who met the study criteria. The samples were divided into groups of T3 and T4 tumor expansion, groups of N1 and N2+ thyroid nodules, as well as groups of positive and negative free margins. These samples were associated with the stomal recurrence and categorized into yes and no accordingly. The Chi-Square Test was employed for correlation analysis and followed by multiple logistic regression. The results were considered correlated if the P-value was less than 0.05. Results: This study obtained 92 patients with 87 males and 5 females. The analysis of the correlation between tumor expansion and stomal recurrence suggested a P-value of 0.770, which was greater than 0.05. Meanwhile, the correlation between thyroid nodules and free margins with stomal recurrence indicated a P-value of 0.068 and 0.147, greater than 0.05. Conclusion: There was no significant correlation between tumor expansion, thyroid nodules, and free margins with stomal recurrence after a total laryngectomy.