Published Paper Details:

Transdermal drug delivery system (TDDS) is an integral part of advanced drug delivery systems. About 75% of drugs are taken orally and are found not to be as effective as desired. To improve such characters there is need to developed transdermal drug delivery system. This advancement in drug delivery offers many advantages over traditional methods. Uniform drug plasma concentration, improved bioavailability, Predetermined rate of drug release, reduction in toxic side effects, painless and easy application and simply removing the patch from the skin if any unwanted effects occur are some of the potential advantages of transdermal drug delivery. Transdermal drug delivery system (TDDS) are very effectively overcome the hepatic first pass metabolism and improve the steady plasma drug concentration. This article gives a brief overview over principles behind transdermal drug delivery, as well as the advantages and disadvantages of transdermal drug delivery systems and describes the factor affecting transdermal permeability of different types of transdermal patches, evaluation parameters.