Published Paper Details:

Aquasomes are circular particles made of calcium phosphate or ceramic diamond coated with a polyhydroxyloligomeric film that function as nanoparticulate carrier systems. Despite their simplicity, aquasomes are three layered self-assembled structures made up of a hard stage crystalline nanostructures core covered with oligomeric film with or without modifications in pH on which biochemically active molecules are adsorbed. The carbohydrate coating prevents the biochemically lively molecules from dehydration and stabilises them, while the solid centre core offers structural stability. Following the synthesis of the solid ceramic core and polyhydroxyoligomeric material coatings such as cellulobiose and trehalose, the final stage was drug packing, in which the aquasomes serve as host particles, non-covalently interacting with the bioactive moiety through hydrogen and cationic bonding. Insulin, haemoglobin, and enzymes such as serratiopeptidase have also been successfully delivered using the delivery mechanism. The concepts of self-assembly, method of planning, characterization, and implementation in various fields of pharmacy are covered in this article.