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Ivy Gourd, Coccinia grandis (L), also known as little gourd or baby watermelon plant, that is a member of the family of Cucurmbitaceae. It is one of the most beneficial medicinal herbs in traditional and ayurvedic medicine. The fruits of Coccinia Grandis are recognized to have active constituents similar to amyran, lupeol, taraxerone, taxerol and glycoside cucurbitacan B. The subsistence of secondary metabolites like alkaloids, flavonoids, saponins, glycosides etc. in the plant may give to their medicinal value. The tender green fruits are nutritious and are a good source of calcium, protein, calcium, fiber and beta carotene, Vitamin-A. It has been used in traditional medicine as a domestic remedy for a variety of diseases. The entire plant of Coccinia grandis having pharmacological actions such as analgesic, antipyretic, anti- inflammatory, antimicrobial, antiulcer, antidiabetic, antioxidant, hypoglycemic, hepatoprotective, antimalarial, antidyslipidemic, anticancer, antitussive, mutagenic. Therefore, the final note emphasizes this plant broadly being used for the treatment of diabetes, jaundice, hypertension, fever and gastrointestinal exertion and to relieve pain. The Coccinia grandis has good likely of medicinal values and chemical constituents.